There’s a unique joy that comes from turning classic comfort food into something even more delectable. Picture this: the irresistible blend of a juicy cheeseburger with the heartiness of a homemade meatloaf. That’s exactly what you get with this Cheeseburger Meatloaf, a dish that’s perfect not just for weeknight dinners, but also a crowd-pleaser at gatherings. When I first decided to marry these two culinary staples, I was captivated by how the sharp cheddar cheese and crispy bacon elevate the flavors, all wonderfully nestled beneath a sweet and tangy ketchup glaze.

Whether you’re looking to add a little zing to your dinner repertoire or simply seeking a cozy meal that will warm your soul, this inventive recipe serves it all up with ease. So let’s dive into this comforting dish that promises a nostalgic dining experience, transforming ordinary nights into something special.

Why Will You Love This Cheeseburger Meatloaf?

Simplicity at Its Best: Preparing this dish is a breeze, perfect for home cooks and professionals alike.

Comfort Food Reimagined: This Cheeseburger Meatloaf combines the best of both worlds, giving you the flavors of a cheeseburger wrapped in a hearty meatloaf.

Layered Flavors: With crispy bacon and sharp cheddar melted into every bite, it’s a flavor explosion you won’t forget.

Crowd-Pleasing: Ideal for family dinners or entertaining guests, this dish brings everyone to the table with its mouthwatering aroma.

Versatile Options: Substitute with turkey or chicken to suit dietary preferences, proving that this recipe can adapt to any kitchen!

Ready to elevate your dinner game? Consider pairing with classic sides like mashed potatoes for a complete comfort meal.

Cheeseburger Meatloaf Ingredients

For the Meatloaf
• Ground Beef – Provides the main protein and structure; use lean ground beef for a healthier option.
• Sharp Cheddar Cheese – Adds rich flavor and moisture; substitute with Monterey Jack for a milder taste.
• Bacon – Enhances the savory profile with added fat and crunch; can use turkey bacon for a lower-fat alternative.
• Onion – Supplies aromatic depth; fresh or powdered can be used interchangeably depending on availability.
• Garlic – Elevates flavor depth with its aromatic quality; fresh minced garlic works best for intensity.
• Breadcrumbs – Helps bind the mixture and adds texture; use gluten-free breadcrumbs for a gluten-free version.
• Egg – Acts as a binder for the meat mixture; a flax egg can be substituted for vegan-friendly options.

For the Glaze
• Ketchup – Used for the glaze, balancing sweetness with tang; swap with barbecue sauce for a different flavor twist.

This delicious Cheeseburger Meatloaf is bound to become a family favorite with its unbeatable combination of flavors!

How to Make Cheeseburger Meatloaf

Preheat the oven to 350°F (175°C). This ensures your meatloaf cooks evenly and develops a deliciously brown crust.
Combine ground beef, finely chopped onion, minced garlic, breadcrumbs, egg, and half of the cheddar cheese in a large bowl. Mix gently until just combined to maintain a tender texture.
Add the chopped bacon into the mixture. The bacon will lend a delightful crunch and rich flavor that will elevate your meatloaf.
Shape the beef mixture into a loaf and place it in a baking dish. Form it evenly so it cooks consistently and holds its shape beautifully.
Prepare the glaze by mixing ketchup and the remaining cheddar cheese in a small bowl, then spread it evenly on top of the loaf. This will caramelize and add a sweet, tangy layer during baking.
Bake in the preheated oven for 60-70 minutes or until the internal temperature reaches 160°F (71°C). You want it juicy but cooked through for safety.
Remove from the oven and let rest for 10 minutes before slicing. This resting period helps juices redistribute, ensuring each slice is moist and flavorful.

Optional: Garnish with fresh parsley for a pop of color and added freshness.

Exact quantities are listed in the recipe card below.

Storage Tips for Cheeseburger Meatloaf

Fridge: Store leftovers in an airtight container for up to 3 days. Make sure to let the meatloaf cool completely before sealing for the best freshness.
Freezer: Wrap the meatloaf tightly in plastic wrap and then foil, or place it in a freezer-safe container to preserve flavor for up to 3 months.
Reheating: For best results, reheat in the oven at 350°F (175°C) until warmed through, about 20 minutes. This will keep the cheeseburger meatloaf moist and delicious.
Room Temperature: Keep the meatloaf out at room temperature for no more than 2 hours to prevent spoilage; always refrigerate leftovers promptly.

Cheeseburger Meatloaf Variations

Feel free to make this comforting dish your own with these delightful twists.

Turkey Alternative: Swap ground beef for ground turkey or chicken for a lighter, lean protein option.
Spicy Kick: Mix in chopped jalapeños for an extra layer of heat that beefs up the flavor profile.
Veggie Boost: Add chopped bell peppers or mushrooms for added texture and flavor, making every bite a surprise.
Cheese Swap: Experiment with different cheeses like pepper jack for a creamy, spicy addition that packs a punch.
Barbecue Glaze: Substitute ketchup with barbecue sauce for a sweet and smoky glaze that brings new dimensions to your meatloaf.
Herb Infusion: Incorporate fresh herbs like parsley or thyme into the meat mixture for a hint of freshness that brightens up the dish.
Gluten-Free Option: Use gluten-free breadcrumbs instead of regular ones to cater to those with gluten sensitivities, all while maintaining that comforting texture.
Flax Egg: Make it vegan-friendly by substituting the egg with a flax egg (1 tablespoon flaxseed meal + 2.5 tablespoons water) to bind the ingredients together.

Expert Tips for Cheeseburger Meatloaf

Mix Gently: Avoid over-mixing the meatloaf mixture to keep it tender. Just combine until ingredients are evenly incorporated.
Thermometer Check: Use a meat thermometer to prevent overbaking; aim for 160°F (71°C) for perfect doneness without drying out your cheeseburger meatloaf.
Resting Time Matters: Let the meatloaf rest for 10 minutes before slicing. This helps it hold together better and boosts juiciness when served.
Experiment with Toppings: Feel free to add different toppings or cheeses for a personal twist, like a spicy pepper jack for an extra kick in your cheeseburger meatloaf!
Serve It Right: Pair with classic sides like mashed potatoes or a fresh salad to create a comforting meal that everyone will love.

Make Ahead Options

These Cheeseburger Meatloaf preparations are perfect for busy home cooks looking to save time during the week! You can prepare the meatloaf mixture and shape it into a loaf up to 24 hours in advance. Simply combine the ground beef, bacon, onions, garlic, breadcrumbs, egg, and half of the cheddar cheese in a bowl, then form it into a loaf and cover tightly with plastic wrap. Refrigerate until you’re ready to cook. For best quality, don’t glaze it with ketchup until you’re ready to bake. When it’s time to serve, just add the topping and bake as directed. This way, you’ll have a mouthwatering, homemade meal with minimal effort!

What to Serve with Cheeseburger Meatloaf?

The perfect meal isn’t complete without the right sides and pairings to elevate your dining experience.

Creamy Mashed Potatoes:
Their fluffy texture and buttery taste complement the savory richness of the meatloaf, creating a comfort food dream combination.
Garlic Green Beans:
The crunch of fresh green beans dressed with garlic provides a vibrant, earthy flavor that balances the hearty meatloaf beautifully.
Classic Coleslaw:
With its crunchy cabbage and creamy dressing, coleslaw adds a refreshing contrast to the warm, meaty loaf, brightening every bite.
Roasted Brussels Sprouts:
Their crispy, caramelized edges and nutty flavors add depth to your plate, enhancing the cheeseburger meatloaf experience to new heights.
Cornbread:
This slightly sweet bread brings a delightful texture and flavor that melds beautifully with the savory aspects of the meatloaf.
Baked Sweet Potatoes:
Sweet potatoes provide a natural sweetness and added nutrition, making them a perfect side that complements the flavors of cheeseburger meatloaf.
Caesar Salad:
The zesty dressing and crunchy romaine lettuce offer a delightful freshness, ensuring each bite is balanced and the meal is satisfying.
Cheddar Biscuits:
Flaky and cheesy, these biscuits make a perfect match, echoing the flavors in the meatloaf while adding their own scrumptiousness.
Iced Tea:
A refreshing glass of iced tea with lemon balances the richness of the meal and is perfect for any occasion!
Chocolate Chip Cookies:
For a sweet finish, indulge in warm chocolate chip cookies that add a touch of nostalgia and comfort to your meal.

Cheeseburger Meatloaf Recipe FAQs

How do I choose the right ground beef for my cheeseburger meatloaf?
Absolutely! For the best cheeseburger meatloaf, I recommend using lean ground beef—like 80/20 chuck—that provides a balance of flavor and fat for moistness. If you want a healthier option, consider using 93/7 lean beef, but keep in mind that it may result in a slightly drier loaf.

What’s the best way to store leftover cheeseburger meatloaf?
Very good question! Store any leftover cheeseburger meatloaf in an airtight container in the refrigerator for up to 3 days. Make sure it’s completely cooled before sealing to keep the flavors intact. You can also reheat slices in the oven at 350°F (175°C) for the best results.

Can I freeze cheeseburger meatloaf, and how should I do it?
Absolutely! To freeze your cheeseburger meatloaf, wrap it tightly in plastic wrap and then in aluminum foil, or place it in a freezer-safe container. It can maintain its flavor for up to 3 months in the freezer. When ready to enjoy, thaw it in the refrigerator overnight and reheat as you would normally.

What if my cheeseburger meatloaf doesn’t hold its shape while baking?
That’s a common concern! If your meatloaf isn’t holding together, it could be due to over-mixing the ingredients, which can result in a dense loaf. To fix this, be sure to mix the ingredients gently. If you still struggle, consider adding a bit more breadcrumb to help with binding, or reduce the moisture content by using slightly less ketchup in the glaze.

Is this cheeseburger meatloaf suitable for those with gluten allergies?
Yes, indeed! To make a gluten-free cheeseburger meatloaf, simply substitute regular breadcrumbs with gluten-free breadcrumbs. Additionally, double-check that your ketchup is gluten-free, as some brands may contain gluten ingredients. Your gluten-free friends will be thrilled to enjoy this dish alongside you!

Can I make this dish in advance?
Certainly! You can prepare the meatloaf mixture up to a day in advance. Just assemble the meatloaf and cover it tightly in plastic wrap or foil in the fridge. When you’re ready to cook, just remove the wrap and spread the glaze on top before baking. This will save you time and still deliver that delicious, comforting flavor!